Ethyl 4-methylthiazole-2-carboxylate

Ethyl 4-methylthiazole-2-carboxylate - Names and Identifiers

Name	2-Thiazolecarboxylicacid, 4-methyl-, ethyl ester
Synonyms	ethyl 4-Methylthiazole-2-carboxylate Ethyl 4-methylthiazole-2-carboxylate 2-(Ethoxycarbonyl)-4-methyl-1,3-thiazole ethyl 4-methyl-1,3-thiazole-2-carboxylate 4-Methylthiazol-2-carbonsaeure-ethylester Ethyl 4-methyl-1,3-thiazole-2-carboxylate 4-Methylthiazole-2-carboxylic acid ethylester 4-Methylthiazole-2-carboxylicacid ethyl ester 4-METHYLTHIAZOLE-2-CARBOXYLIC ACID ETHYLESTER 4-Methyl-2-thiazolecarboxylic acid ethyl ester 2-Thiazolecarboxylicacid, 4-methyl-, ethyl ester 2-Thiazolecarboxylic acid, 4-methyl-, ethyl ester
CAS	7210-73-3

Ethyl 4-methylthiazole-2-carboxylate - Physico-chemical Properties

Molecular Formula	C7H9NO2S
Molar Mass	171.22
Density	1.198±0.06 g/cm3(Predicted)
Boling Point	130-132 °C(Press: 16 Torr)
Flash Point	104.2 °C
pKa	0.85±0.10(Predicted)
Storage Condition	2-8°C

Ethyl 4-methylthiazole-2-carboxylate - Introduction

2-Thiazolecarboxylicacid, 4-methyl-, ethyl ester is an organic compound with the chemical formula C9H9NO2S. The following is a description of its nature, use, preparation and safety information:

Nature:
2-Thiazolecarboxylicacid, 4-methyl-, ethyl ester is a colorless or light yellow liquid with a special smell. It is soluble in organic solvents such as ethanol and ether at room temperature, but has low solubility in water. Its boiling point is about 235°C.

Use:
2-Thiazolecarboxylicacid, 4-methyl-, ethyl ester has a wide range of applications in organic synthesis. It can be used as an important intermediate for the synthesis of a variety of drugs, spices and pesticides, especially some drugs with antibacterial, antiviral and antitumor activity. In addition, it can also be used for synthetic dyes, rubber additives and coatings.

Preparation Method:
2-Thiazolecarboxylicacid, 4-methyl-, ethyl ester can be prepared by isomerization of thiazole. Specifically, 4-methylthiazole-2-carboxylic acid is reacted with an alcohol (e. g., ethanol) to form an ester under acid catalysis.

Safety Information:
2-Thiazolecarboxylicacid, 4-methyl-, ethyl ester is irritating, avoid skin contact and inhalation of gas. Appropriate protective equipment, such as gloves and face masks, should be worn during use. In addition, care should be taken to avoid contact with strong oxidizing agents and strong basic substances. In the event of an accidental leak, appropriate clean-up measures should be taken immediately.

Last Update：2024-04-09 20:52:54